Qvar vs. Flovent: Differences, Interactions, and Side Effects

Qvar vs. Flovent

Qvar and Flovent are prescription medications used to curb symptoms of asthma. They are both inhaled corticosteroids, which control mild persistent asthma by reducing inflammation in the lungs. Qvar and Flovent are control inhalers, which means that they are used regularly as directed by the patient’s prescription, and cannot be used during asthma attacks.

Asthma is one of the most common and costly diseases in the United States. Approximately 25 million people or 1 in 13 in the U.S. have asthma. Asthma is more common in female adults than male adults. Around 9.8% of female adults have asthma, compared to 6.1% of male adults.

Although asthma cannot be cured completely, there are many steps one can take to prevent asthma attacks, control symptoms, and stay healthy. Patients can use long-term control medications such as Qvar and Flovent, fast-acting rescue medications for asthma attacks, and allergy medications for treating allergic asthma.  They can also make simple changes to their lifestyle such as regularly cleaning their house to decrease dust buildup, avoiding allergens that may further trigger asthma, doing regular physical activity, and controlling comorbidities that may worsen asthma symptoms.

Qvar

Qvar is a prescription medicine used as a maintenance treatment for the prevention and control of asthma in people 4 years of age and older. 

Qvar RediHaler is an inhalation corticosteroid with beclomethasone as the active ingredient. Qvar is not a rescue inhaler. It will not work fast enough to treat an asthma attack.

Qvar uses and side effects (video)

Flovent

Flovent is a prescription inhaled corticosteroid medicine for the long-term treatment of asthma in people aged 4 years and older. Flovent is not used to relieve sudden breathing problems and won’t replace a rescue inhaler.

Flovent is an inhaled corticosteroid with fluticasone as the active ingredient. It lowers inflammation in your lungs, which controls asthma and prevents asthma attacks.

Flovent uses and side effects (video)

Check out other Drug vs. Drug articles here.

Differences

Qvar and Flovent are both used to treat persistent asthma symptoms, but there are some key differences.

Active Ingredients

Qvar contains the active ingredient beclomethasone, while Flovent contains fluticasone.

Name and Manufacturer

Qvar is manufactured by Teva Pharmaceutical Industries and is known as beclomethasone dipropionate HFA, while Flovent is manufactured by GSK and is known as fluticasone propionate inhalation aerosol.

Form

Both Qvar and Flovent come as metered-dose inhalation aerosols, but Flovent is also available as a dry powder inhaler under the brand name Flovent Diskus.

Strength

Qvar RediHalers are available in strengths of 40 and 80 micrograms (mcg) per actuation.

Flovent HFA inhalers come in strengths of 44, 110, and 220 mcg per actuation, and the Flovent Diskus comes in strengths of 50, 100, and 250 mcg per foil pouch.

Qvar Flovent
Inhaled corticosteroidDrug ClassInhaled corticosteroid
BeclomethasoneTypeFluticasone
Mild to moderate persistent asthmaConditions TreatedMild to moderate persistent asthma
Beclomethasone dipropionateGeneric FormFluticasone propionate
Qvar RediHaler (aerosol inhaler)Different FormsFlovent HFA (aerosol inhaler) and Flovent Diskus (dry powder inhaler)
Twice daily, at the same time every dayAdministrationTwice daily, at the same time every day
As long as required, could be indefiniteHow long is the typical treatment?As long as required, could be indefinite
Adults and children 4 years or olderWho can use the medication?Adults and children 4 years or older
Qvar vs. Flovent: Differences

Dosing

Qvar RediHaler

4-11 years of age:

Patient’s Previous TherapyRecommended Starting DoseMaximum Dose
Bronchodilators Alone40 mcg twice daily80 mcg twice daily
source: https://hcp.qvar.com/dosing/

12 years or older:

Patient’s Previous TherapyRecommended Starting DoseMaximum Dose
Bronchodilators Alone40-80 mcg twice daily320 mcg twice daily
Inhaled Corticosteroids40-320 mcg twice daily320 mcg twice daily
source: https://hcp.qvar.com/dosing/

Flovent HFA

AgeRecommended Dose
4-11 years44 mcg twice daily about 12 hours apart
12 years or older (not already on inhaled corticosteroid)44 mcg twice daily about 12 hours apart, the maximum dose is 440 mcg twice daily
source: https://www.drugs.com/dosage/flovent.html

Flovent Diskus

AgeRecommended DoseMaximum Dose
4-11 years50 mcg twice daily about 12 hours apart100 mcg twice daily about 12 hours apart
12 years or older100 mcg twice daily about 12 hours apart1000 mcg twice daily about 12 hours apart
source: ​​https://www.drugs.com/dosage/flovent-diskus.html

Which One is More Effective?

If used regularly, both Qvar and Flovent are effective for controlling asthma symptoms. A study conducted by Bootsma, Dekhuijzen, Festen, Mulder, and van Herwaarden came to the conclusion that fluticasone propionate (Flovent), is twice as effective as beclomethasone dipropionate (Qvar) at controlling bronchial sensitivity in asthma patients.

There are also combination inhalers such as Advair and Symbicort, which have been proven to be effective in clinical trials. They act as both an inhaled corticosteroid and bronchodilator, and they may be prescribed if asthma symptoms don’t get better after consistent treatment with only corticosteroids.

Interactions

Many drugs interact with other drugs in ways that can lead to unprecedented health outcomes. Here are some of the main drugs that Qvar and Flovent interact with:

  • Protease inhibitors such as Amprenavir and Atazanavir
  • CYP3A4 inhibitors such as Clarithromycin, Indinavir, Itraconazole, Nefazodone, Nelfinavir, Ritonavir, and Saquinavir
  • Tobacco
  • Gene therapy medications such as Yescarta and Tecartus
  • Monoclonal antibodies such as Dinutuximab
  • Immunosuppressants such as Cyclosporine, Azathioprine, and Methotrexate

This may not be a comprehensive list, so make sure to check with your doctor before using Qvar or Flovent. 

Side Effects

Although Qvar and Flovent are both mostly safe for patients without any contraindications, common side effects of both drugs include:

  • Upper Respiratory Tract Infection (URTI)
  • Yeast infection in the mouth
  • Throat pain
  • Hay fever
  • Sinus irritation

If you ever experience any serious side effects, talk to a doctor and seek medical attention immediately. More serious side effects include:

  • Oral thrush
  • Worsening asthma or asthma attacks
  • Adrenal insufficiency
  • Bronchospasm or wheezing
  • Allergic reactions
  • Immunosuppression
  • Slowed growth in children
  • Eye problems
  • Lower bone density or osteoporosis

Conclusion

Overall, Qvar and Flovent are both generally effective at controlling asthma symptoms, but they definitely have differences. It’s important to examine those differences and talk to a physician before choosing which one to take, and to make sure that you don’t have any contraindications or take any medication with negative interactions. If you experience any side effects for long periods of time, make sure to go to a doctor.

FAQs

What is Qvar RediHaler?

Qvar RediHaler is an inhalation aerosol taken twice daily and designed to regulate symptoms of asthma. It is an inhaled corticosteroid with beclomethasone as the active ingredient.

What is Flovent HFA?

Flovent HFA is an inhalation aerosol taken twice daily that controls asthma symptoms. Its active ingredient is fluticasone and it is an inhaled corticosteroid.

Who can take Qvar and Flovent?

Qvar RediHaler, Flovent HFA, and Flovent Diskus are approved by the FDA for patients ages 4 and up. Qvar, Flovent, and most asthma medicines are also safe for pregnant patients if taken as directed by a physician.

How much do Qvar and Flovent cost?

Both Qvar and Flovent only come in brand-name forms, so their costs are relatively high. Without insurance, Qvar RediHaler costs about $544 on average, while Flovent HFA and Flovent Diskus cost around $217 and $176 respectively.

Posted by
Qwark

Qwark writing staff is a team of pharmacists, nurse practitioners, and doctors.

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